根据ProtScale 预测结果,如何判断蛋白质序列的疏水性
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根据ProtScale 预测结果,如何判断蛋白质序列的疏水性
Using the scale Hphob./ Kyte & Doolittle,the individual values for the 20 amino acids are:
Ala:1.800 Arg:-4.500 Asn:-3.500 Asp:-3.500 Cys:2.500 Gln:-3.500
Glu:-3.500 Gly:-0.400 His:-3.200 Ile:4.500 Leu:3.800 Lys:-3.900
Met:1.900 Phe:2.800 Pro:-1.600 Ser:-0.800 Thr:-0.700 Trp:-0.900
Tyr:-1.300 Val:4.200 :-3.500 :-3.500 :-0.490
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Weights for window positions 1,..,21,using linear weight variation model:
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
edge center edge
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MIN:-1.724
MAX:1.052
请问怎么判断此序列是不是具有疏水性?从图中看是数值要达到多少值才行吗?具体是多少?
![](http://img.wesiedu.com/upload/4/2a/42a6bd89ced1f63be262f89d34e88abf.jpg)
Using the scale Hphob./ Kyte & Doolittle,the individual values for the 20 amino acids are:
Ala:1.800 Arg:-4.500 Asn:-3.500 Asp:-3.500 Cys:2.500 Gln:-3.500
Glu:-3.500 Gly:-0.400 His:-3.200 Ile:4.500 Leu:3.800 Lys:-3.900
Met:1.900 Phe:2.800 Pro:-1.600 Ser:-0.800 Thr:-0.700 Trp:-0.900
Tyr:-1.300 Val:4.200 :-3.500 :-3.500 :-0.490
________________________________________
Weights for window positions 1,..,21,using linear weight variation model:
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
edge center edge
________________________________________
MIN:-1.724
MAX:1.052
请问怎么判断此序列是不是具有疏水性?从图中看是数值要达到多少值才行吗?具体是多少?
![](http://img.wesiedu.com/upload/4/2a/42a6bd89ced1f63be262f89d34e88abf.jpg)
![根据ProtScale 预测结果,如何判断蛋白质序列的疏水性](/uploads/image/z/16714133-53-3.jpg?t=%E6%A0%B9%E6%8D%AEProtScale+%E9%A2%84%E6%B5%8B%E7%BB%93%E6%9E%9C%2C%E5%A6%82%E4%BD%95%E5%88%A4%E6%96%AD%E8%9B%8B%E7%99%BD%E8%B4%A8%E5%BA%8F%E5%88%97%E7%9A%84%E7%96%8F%E6%B0%B4%E6%80%A7)
可能是比较中性,Val疏水值都到4.200了,MAX才1.052
mark,望高人解答.
mark,望高人解答.