————the beginnig of the 19th century did scientists know tha

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————the beginnig of the 19th century did scientists know that all matter is made up of atoms .
a.at b .by c.up to d.not until

我的看法意见,
分析:答案A,at the begining of,翻译成:"在.前期",这个短语可放置句首,且不用倒装.
答案B,By the begining of,表示:到.初,放句首不用倒装,
而NOT UNTIL,则表示:直到.为止,没有这种搭配,故A.B.C淘汰,
答案C,UP TO,可释义为:到.为止,放置句首需倒装,且符合语义.选C.
Best regards
Regina

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